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翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Gene therapy in Parkinson's disease ： ウィキペディア英語版 Gene therapy in Parkinson's disease Gene therapy in Parkinson disease consists in the creation of new cell that produces a specific neurotransmitter (dopamine), protect the neural system, or the modification of gene’s that are related to the disease. Then these cells are transplanted to a patient with the disease. There are different kinds of treatments that focus on reducing the symptoms of the disease but currently there is no cure. ==Current treatments== Parkinson's disease (PD) is a progressive neurological condition result of the death of the cell that contains and produces dopamine in substantia nigra. People with PD may develop disturbance in their motor activities. Some activities can be tremor or shaking, rigidity and slow movements (bradykinesia). Patients may eventually present certain psychiatric problems like depression and dementia. Current pharmacological intervention consist on the administration of L-dopa, a dopamine precursor. The L-Dopa therapy increases dopamine production of the remaining nigral neurons.〔 Other therapy is the deep brain electrical stimulation to modulate the overactivity of the subthalamic nucleus to the loss of dopamine signaling in the stratum. However, with this treatment the number of substantia nigra neurons decrease so it becomes less efficient. These treatments try to reduce the symptoms of the patient focusing on increasing the production of dopamine but they do not cure the disease. The new treatments for PD are in clinical trials and most of them are centered on gene therapy. With this, researchers expect to compensate the loss of dopamine or to protect the dopamine neurons from degeneration.〔 The pharmacological and surgical therapies for PD focus on compensating the ganglia dysfunction caused by the degeneration of the dopaminergic neuron from substantia nigra.〔 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Gene therapy in Parkinson's disease」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.